The Existing Drug Vorinostat as a New Lead Against Cryptosporidiosis by Targeting the Parasite Histone Deacetylases
Author(s) -
Fengguang Guo,
Haili Zhang,
Nina McNair,
Jan R. Mead,
Guan Zhu
Publication year - 2017
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jix689
Subject(s) - vorinostat , histone , drug , histone deacetylase , biology , cancer research , pharmacology , genetics , dna
Cryptosporidiosis affects all human populations, but can be much more severe or life-threatening in children and individuals with weak or weakened immune systems. However, current options to treat cryptosporidiosis are limited.
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