Open AccessDifferentially Expressed Intrahepatic Genes Contribute to Control of Hepatitis B Virus Replication in the Inactive Carrier Phase
Author(s) -
Hongyan Liu,
Fahong Li,
XiaoYong Zhang,
Jie Yu,
Jinyu Wang,
Jia Jia,
Xueping Yu,
Zhongliang Shen,
Zhenghong Yuan,
Xiaonan Zhang,
Zhanqing Zhang,
Xinxin Zhang,
Lungen Lu,
Hai Li,
Mengji Lu,
Jiming Zhang
Publication year - 2017
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jix683
Subject(s) - hepatitis b virus , viral replication , biology , virology , immune system , transcriptome , gene , virus , microarray , hepatitis b , gene expression , immunology , genetics
The natural history of chronic hepatitis B virus (HBV) infection was divided into 4 phases. Patients in the inactive carrier (IC) status and immune tolerant (IT) phase had normal alanine aminotransferase levels but huge different viral loads. The mechanism underlying low viral replication status in IC phase is unknown.
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