Limited Impact of Adolescent Meningococcal ACWY Vaccination on Neisseria meningitidis Serogroup W Carriage in University Students | Zendy

Neil J. Oldfield | Zendy; Luke R. Green | Zendy; Julian Parkhill | Zendy; Christopher D. Bayliss | Zendy; David P. J. Turner | Zendy

Open Access

Limited Impact of Adolescent Meningococcal ACWY Vaccination on Neisseria meningitidis Serogroup W Carriage in University Students

Author(s) -

Neil J. Oldfield,

Luke R. Green,

Julian Parkhill,

Christopher D. Bayliss,

David P. J. Turner

Publication year - 2017

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jix596

Subject(s) - neisseria meningitidis , carriage , vaccination , meningococcal disease , immunization , meningococcal vaccine , virology , biology , multilocus sequence typing , whole genome sequencing , genome , medicine , gene , antigen , genetics , genotype , bacteria , pathology

In the United Kingdom, rising levels of disease due to Neisseria meningitidis serogroup W clonal complex (cc) sequence type (ST) 11 (MenW:cc11) strains led to introduction of meningococcal conjugate vaccine (MenACWY) for teenagers. We investigated the impact of immunization on carriage of meningococci targeted by the vaccine, using whole-genome sequencing of isolates recovered from a cohort of vaccinated university students.

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