Severe Influenza Is Characterized by Prolonged Immune Activation: Results From the SHIVERS Cohort Study | Zendy

SookSan Wong | Zendy; Christine M. Oshansky | Zendy; Xi-zhi J. Guo | Zendy; Jacqui Ralston | Zendy; Timothy Wood | Zendy; Ruth Seeds | Zendy; E. Claire Newbern | Zendy; Ben Waite | Zendy; Gary Reynolds | Zendy; MarcAlain Widdowson | Zendy; Q. Sue Huang | Zendy; Richard J. Webby | Zendy; Paul G. Thomas | Zendy; for the SHIVERS Investigation Team | Zendy; Nikki Turner | Zendy; Michael G. Baker | Zendy; Cameron Grant | Zendy; Colin McArthur | Zendy; Sally Roberts | Zendy; Adrian Trenholmes | Zendy; Conroy Wong | Zendy; Susan Taylor | Zendy; Mark G. Thompson | Zendy; Diane Gross | Zendy; Jazmin Duque | Zendy; Kathryn Haven | Zendy; Debbie Aley | Zendy; Pamela Muponisi | Zendy; Bhamita Chand | Zendy; Yan Chen | Zendy; L. W. Plewes | Zendy; Frann Sawtell | Zendy; Shirley Lawrence | Zendy; Reniza Cogcoy | Zendy; J. R. Smith | Zendy; Franie Gravidez | Zendy; Mandy Ma | Zendy; Shona Chamberlin | Zendy; Kirstin Davey | Zendy; Tania Knowles | Zendy; Jo-Ann McLeish | Zendy; Angela Todd | Zendy; Judy Bocacao | Zendy; Wendy Gunn | Zendy; Pamela Kawakami | Zendy; Susan Walker | Zendy; Robyn Madge | Zendy; Nora Moore | Zendy; Fahimeh Rahnama | Zendy; Helen Qiao | Zendy; Fifi Tse | Zendy; Mahtab Zibaei | Zendy; Tirzah Korrapadu | Zendy; Louise Optland | Zendy; Cecilia Dela Cruz | Zendy

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Severe Influenza Is Characterized by Prolonged Immune Activation: Results From the SHIVERS Cohort Study

Author(s) -

SookSan Wong,

Christine M. Oshansky,

Xi-zhi J. Guo,

Jacqui Ralston,

Timothy Wood,

Ruth Seeds,

E. Claire Newbern,

Ben Waite,

Gary Reynolds,

MarcAlain Widdowson,

Q. Sue Huang,

Richard J. Webby,

Paul G. Thomas,

for the SHIVERS Investigation Team,

Nikki Turner,

Michael G. Baker,

Cameron Grant,

Colin McArthur,

Sally Roberts,

Adrian Trenholmes,

Conroy Wong,

Susan Taylor,

Mark G. Thompson,

Diane Gross,

Jazmin Duque,

Kathryn Haven,

Debbie Aley,

Pamela Muponisi,

Bhamita Chand,

Yan Chen,

L. W. Plewes,

Frann Sawtell,

Shirley Lawrence,

Reniza Cogcoy,

J. R. Smith,

Franie Gravidez,

Mandy Ma,

Shona Chamberlin,

Kirstin Davey,

Tania Knowles,

Jo-Ann McLeish,

Angela Todd,

Judy Bocacao,

Wendy Gunn,

Pamela Kawakami,

Susan Walker,

Robyn Madge,

Nora Moore,

Fahimeh Rahnama,

Helen Qiao,

Fifi Tse,

Mahtab Zibaei,

Tirzah Korrapadu,

Louise Optland,

Cecilia Dela Cruz

Publication year - 2017

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jix571

Subject(s) - immunology , proinflammatory cytokine , immune system , cytokine , tumor necrosis factor alpha , cd8 , interleukin , medicine , acquired immune system , inflammation , biology

The immunologic factors underlying severe influenza are poorly understood. To address this, we compared the immune responses of influenza-confirmed hospitalized individuals with severe acute respiratory illness (SARI) to those of nonhospitalized individuals with influenza-like illness (ILI).

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