Open AccessEbola Virus Inactivation by Detergents Is Annulled in Serum
Author(s) -
Jeroen J. A. van Kampen,
Andrei N. Tintu,
Henk Russcher,
Pieter L. A. Fraaij,
Chantal Reusken,
Mikel Rijken,
Jaap J. van Hellemond,
Perry J.J. van Genderen,
Rob Koelewijn,
Menno D. de Jong,
Elaine Haddock,
Robert J. Fischer,
Vincent J. Munster,
Marion Koopmans
Publication year - 2017
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jix401
Subject(s) - ebola virus , titer , virology , virus , herpes simplex virus , whole blood , sodium dodecyl sulfate , virus quantification , microbiology and biotechnology , biology , medicine , chemistry , immunology , chromatography
Treatment of blood samples from hemorrhagic fever virus (HFV)-infected patients with 0.1% detergents has been recommended for virus inactivation and subsequent safe laboratory testing. However, data on virus inactivation by this procedure are lacking. Here we show the effect of this procedure on diagnostic test results and infectious Ebola virus (EBOV) titers.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom