Open AccessNaturally Occurring Single Amino Acid Substitution in the L1 Major Capsid Protein of Human Papillomavirus Type 16: Alteration of Susceptibility to Antibody-Mediated Neutralization
Author(s) -
Tingting Ning,
Aaron Wolfe,
Jianhui Nie,
Weijin Huang,
Xiaojiang S. Chen,
Youchun Wang
Publication year - 2017
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jix274
Subject(s) - capsid , neutralization , antibody , amino acid substitution , virology , human papillomavirus , amino acid , chemistry , biology , substitution (logic) , virus , immunology , biochemistry , medicine , mutation , gene , programming language , computer science
Each vaccine for human papillomavirus type 16 (HPV16) has been developed on the basis of a single variant, and whether these vaccines can prevent infection due to naturally occurring variants was not clear.
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