Open AccessReducedTreponema pallidum–Specific Opsonic Antibody Activity in HIV-Infected Patients With Syphilis
Author(s) -
Christina M. Marra,
Lauren C. Tantalo,
Sharon K. Sahi,
Shelia B. Dunaway,
Sheila A. Lukehart
Publication year - 2015
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jiv591
Subject(s) - treponema , syphilis , opsonin , rapid plasma reagin , virology , immunology , neurosyphilis , sexually transmitted disease , antibody opsonization , biology , medicine , antibody , microbiology and biotechnology , human immunodeficiency virus (hiv)
Human immunodeficiency virus (HIV)-infected individuals may have poorer serological responses to syphilis treatment and may be more likely to experience neurosyphilis. Treponema pallidum is cleared from sites of infection by opsonization, ingestion, and killing by macrophages.
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