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Antigenic characterization of influenza viruses is typically based on hemagglutination inhibition (HI) assay data for viral isolates tested against strain-specific postinfection ferret antisera. Here, similar virus characterizations were performed using serological data from humans with primary influenza A(H3N2) infection.

Antigenic Maps of Influenza A(H3N2) Produced With Human Antisera Obtained After Primary Infection