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Molecular Epidemiology of Infant Botulism in California and Elsewhere, 1976–2010
Author(s) -
Haydee A. Dabritz,
Karen K. Hill,
Jason R. Barash,
Lawrence O. Ticknor,
Charles H. Helma,
Nir Dover,
Jessica R. Payne,
Stephen S. Ar
Publication year - 2014
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jiu331
Subject(s) - amplified fragment length polymorphism , clostridium botulinum , botulism , biology , molecular epidemiology , clade , population , microbiology and biotechnology , genotype , veterinary medicine , toxin , genetic diversity , medicine , phylogenetics , genetics , gene , environmental health
Infant botulism (IB), first identified in California in 1976, results from Clostridium botulinum spores that germinate, multiply, and produce botulinum neurotoxin (BoNT) in the immature intestine. From 1976 to 2010 we created an archive of 1090 BoNT-producing isolates consisting of 1012 IB patient (10 outpatient, 985 hospitalized, 17 sudden death), 25 food, 18 dust/soils, and 35 other strains.

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