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Differences in Antibody Responses Between Trivalent Inactivated Influenza Vaccine and Live Attenuated Influenza Vaccine Correlate With the Kinetics and Magnitude of Interferon Signaling in Children
Author(s) -
Raquel Giacomelli Cao,
Nicolás M. Suárez,
Gerlinde Obermoser,
Santiago M. C. Lopez,
Emilio Flaño,
Sara Mertz,
Randy A. Albrecht,
Adolfo Garcı́a-Sastre,
Asunción Mejías,
Hui Xu,
Huanying Qin,
Derek Blankenship,
Karolina Palucka,
Virginia Pascual,
Octavio Ramilo
Publication year - 2014
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jiu079
Subject(s) - influenza vaccine , virology , antibody , vaccination , interferon , attenuated vaccine , immunology , live attenuated influenza vaccine , microbiology and biotechnology , biology , medicine , virulence , gene , biochemistry
Live attenuated influenza vaccine (LAIV) and trivalent inactivated influenza vaccine (TIV) are effective for prevention of influenza virus infection in children, but the mechanisms associated with protection are not well defined.

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