Delayed Hemolysis After Treatment With Parenteral Artesunate in African Children With Severe Malaria—A Double-center Prospective Study | Zendy

Thierry Rolling | Zendy; Tsiri Agbenyega | Zendy; Saadou Issifou | Zendy; Ayôla Akim Adégnika | Zendy; Justice Sylverken | Zendy; Dorothee Spahlinger | Zendy; Daniel Ansong | Zendy; Sascha J. Z. Löhr | Zendy; Gerd Burchard | Zendy; Jürgen May | Zendy; Benjamin Mordmüller | Zendy; Sanjeev Krishna | Zendy; Peter G. Kremsner | Zendy; Jakob P. Cramer | Zendy

Open Access

Delayed Hemolysis After Treatment With Parenteral Artesunate in African Children With Severe Malaria—A Double-center Prospective Study

Author(s) -

Thierry Rolling,

Tsiri Agbenyega,

Saadou Issifou,

Ayôla Akim Adégnika,

Justice Sylverken,

Dorothee Spahlinger,

Daniel Ansong,

Sascha J. Z. Löhr,

Gerd Burchard,

Jürgen May,

Benjamin Mordmüller,

Sanjeev Krishna,

Peter G. Kremsner,

Jakob P. Cramer

Publication year - 2013

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jit841

Subject(s) - artesunate , medicine , malaria , hemolysis , complication , incidence (geometry) , pediatrics , parasitemia , glucose 6 phosphate dehydrogenase deficiency , prospective cohort study , clinical trial , surgery , immunology , plasmodium falciparum , physics , optics

Parenteral artesunate is recommended as first-line therapy for severe malaria. While its efficacy is firmly established, data on safety are still incomplete. Delayed hemolysis has been described in hyperparasitemic nonimmune travelers, but it is unknown if African children are equally at risk.

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