Natural Cytotoxicity Receptor–Dependent Natural Killer Cytolytic activity Directed at Hepatitis C Virus (HCV) Is Associated With Liver Inflammation, African American Race, IL28B Genotype, and Response to Pegylated Interferon/Ribavirin Therapy in Chronic HCV Infection
Author(s) -
Qinglai Meng,
M.R. Sandhya Rani,
Julia M. Sugalski,
Chelsey J. Judge,
Sarah Phat,
Benigno Rodríguez,
Ronald E. Blanton,
Donald D. Anthony
Publication year - 2013
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jit677
Subject(s) - ribavirin , pegylated interferon , hepatitis c virus , immunology , cytolysis , cytotoxicity , hepatitis c , virology , interferon , natural killer cell , medicine , virus , biology , biochemistry , in vitro
Natural killer (NK) cells are implicated in the pathogenesis of hepatitis C virus (HCV) infection and outcome of interferon (IFN)-α based therapy, although mechanisms remain unclear.
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