The Effect of Chronic Cytomegalovirus Infection on Pneumococcal Vaccine Responses | Zendy

Daniel O’Connor | Zendy; Johannes Trück | Zendy; Rajeka Lazarus | Zendy; Elizabeth Clutterbuck | Zendy; Merryn Voysey | Zendy; Katie Jeffery | Zendy; Andrew J. Pollard | Zendy

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The Effect of Chronic Cytomegalovirus Infection on Pneumococcal Vaccine Responses

Author(s) -

Daniel O’Connor,

Johannes Trück,

Rajeka Lazarus,

Elizabeth Clutterbuck,

Merryn Voysey,

Katie Jeffery,

Andrew J. Pollard

Publication year - 2013

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jit673

Subject(s) - cytomegalovirus , medicine , immunology , pneumococcal vaccine , pneumococcal infections , immune system , streptococcus pneumoniae , pneumococcal disease , cytomegalovirus infections , virology , human cytomegalovirus , viral disease , herpesviridae , virus , biology , antibiotics , microbiology and biotechnology

Immune function declines with age and has been associated with reduced vaccine responsiveness. Chronic infection with cytomegalovirus (CMV) has been proposed as a contributor to poorer responses in older adults. A pneumococcal vaccine has been recommended in the United Kingdom for those aged >65 years since 2003 to prevent pneumococcal disease.

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