Native Efflux Pumps Contribute Resistance to Antimicrobials of Skin and the Ability of Staphylococcus aureus to Colonize Skin | Zendy

Q. C. Truong-Bolduc | Zendy; R. Villet | Zendy; Zoe Estabrooks | Zendy; David C. Hooper | Zendy

Open Access

Native Efflux Pumps Contribute Resistance to Antimicrobials of Skin and the Ability of Staphylococcus aureus to Colonize Skin

Author(s) -

Q. C. Truong-Bolduc,

R. Villet,

Zoe Estabrooks,

David C. Hooper

Publication year - 2013

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jit660

Subject(s) - efflux , staphylococcus aureus , microbiology and biotechnology , biology , antimicrobial , mutant , fatty acid , biochemistry , skin infection , bacteria , gene , genetics

Staphylococcus aureus colonizes skin in the presence of antimicrobial fatty acids and polyamines. The chromosomally encoded Tet38 efflux transporter confers resistance to tetracycline and fitness in abscesses, but its natural substrates and those of the Nor quinolone efflux pumps are unknown.

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