Evaluation of a Human BCG Challenge Model to Assess Antimycobacterial Immunity Induced by BCG and a Candidate Tuberculosis Vaccine, MVA85A, Alone and in Combination | Zendy

S. Harris | Zendy; Joel N. Meyer | Zendy; Iman Satti | Zendy; Leanne Marsay | Zendy; Ian Poulton | Zendy; Richard Tanner | Zendy; Angela M. Minassian | Zendy; Helen A. Fletcher | Zendy; Helen McShane | Zendy

Open Access

Evaluation of a Human BCG Challenge Model to Assess Antimycobacterial Immunity Induced by BCG and a Candidate Tuberculosis Vaccine, MVA85A, Alone and in Combination

Author(s) -

S. Harris,

Joel N. Meyer,

Iman Satti,

Leanne Marsay,

Ian Poulton,

Richard Tanner,

Angela M. Minassian,

Helen A. Fletcher,

Helen McShane

Publication year - 2013

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jit647

Subject(s) - antimycobacterial , bcg vaccine , tuberculosis , tuberculosis vaccines , immunology , immunity , vaccination , medicine , mycobacterium tuberculosis , virology , immune system , pathology

A new vaccine is urgently needed to combat tuberculosis. However, without a correlate of protection, selection of the vaccines to take forward into large-scale efficacy trials is difficult. Use of bacille Calmette-Guérin (BCG) as a surrogate for human Mycobacterium tuberculosis challenge is a novel model that could aid selection.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research