Changes in Malaria Parasite Drug Resistance in an Endemic Population Over a 25-Year Period With Resulting Genomic Evidence of Selection | Zendy

Davis Nwakanma | Zendy; Craig W. Duffy | Zendy; Alfred AmambuaNgwa | Zendy; Eniyou Oriero | Zendy; Kalifa Bojang | Zendy; Margaret Pinder | Zendy; Chris Drakeley | Zendy; Colin J. Sutherland | Zendy; Paul Milligan | Zendy; Bronwyn MacInnis | Zendy; Dominic Kwiatkowski | Zendy; Taane G. Clark | Zendy; Brian Greenwood | Zendy; David J. Conway | Zendy

Open Access

Changes in Malaria Parasite Drug Resistance in an Endemic Population Over a 25-Year Period With Resulting Genomic Evidence of Selection

Author(s) -

Davis Nwakanma,

Craig W. Duffy,

Alfred AmambuaNgwa,

Eniyou Oriero,

Kalifa Bojang,

Margaret Pinder,

Chris Drakeley,

Colin J. Sutherland,

Paul Milligan,

Bronwyn MacInnis,

Dominic Kwiatkowski,

Taane G. Clark,

Brian Greenwood,

David J. Conway

Publication year - 2013

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jit618

Subject(s) - biology , drug resistance , malaria , genetics , single nucleotide polymorphism , plasmodium falciparum , population , dhps , genome , allele , gene , genotype , medicine , immunology , environmental health

Analysis of genome-wide polymorphism in many organisms has potential to identify genes under recent selection. However, data on historical allele frequency changes are rarely available for direct confirmation.

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