Evaluation of Serologic and Antigenic Relationships Between Middle Eastern Respiratory Syndrome Coronavirus and Other Coronaviruses to Develop Vaccine Platforms for the Rapid Response to Emerging Coronaviruses | Zendy

Sudhakar Agnihothram | Zendy; Robin Gopal | Zendy; Boyd L. Yount | Zendy; Eric Donaldson | Zendy; Vineet D. Menachery | Zendy; Rachel L. Graham | Zendy; Trevor Scobey | Zendy; Lisa E. Gralinski | Zendy; Mark R. Denison | Zendy; Maria Zambon | Zendy; Ralph S. Baric | Zendy

Open Access

Evaluation of Serologic and Antigenic Relationships Between Middle Eastern Respiratory Syndrome Coronavirus and Other Coronaviruses to Develop Vaccine Platforms for the Rapid Response to Emerging Coronaviruses

Author(s) -

Sudhakar Agnihothram,

Robin Gopal,

Boyd L. Yount,

Eric Donaldson,

Vineet D. Menachery,

Rachel L. Graham,

Trevor Scobey,

Lisa E. Gralinski,

Mark R. Denison,

Maria Zambon,

Ralph S. Baric

Publication year - 2013

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jit609

Subject(s) - virology , middle east respiratory syndrome coronavirus , coronavirus , epitope , biology , serology , middle east respiratory syndrome , antigen , betacoronavirus , coronaviridae , virus , plaque reduction neutralization test , immunodominance , neutralization , antibody , immunology , disease , medicine , infectious disease (medical specialty) , covid-19 , pathology

Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012, causing severe acute respiratory disease and pneumonia, with 44% mortality among 136 cases to date. Design of vaccines to limit the virus spread or diagnostic tests to track newly emerging strains requires knowledge of antigenic and serologic relationships between MERS-CoV and other CoVs.

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