Human Natural Killer Cells Acting as Phagocytes Against Candida albicans and Mounting an Inflammatory Response That Modulates Neutrophil Antifungal Activity
Author(s) -
Jessica Voigt,
Kerstin Hünniger,
Maria Bouzani,
Ilse D. Jacobsen,
Dagmar Barz,
Bernhard Hube,
Jürgen Löffler,
Oliver Kurzai
Publication year - 2013
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jit574
Subject(s) - candida albicans , degranulation , biology , phagocytosis , microbiology and biotechnology , proinflammatory cytokine , natural killer cell , tumor necrosis factor alpha , cytotoxic t cell , phagocyte , corpus albicans , innate immune system , immunology , immune system , inflammation , in vitro , biochemistry , receptor
Natural killer (NK) cells are innate lymphocytes with potent cytotoxic activity. Whereas activity of NK cells has been demonstrated against the fungal pathogens Aspergillus fumigatus and Cryptococcus neoformans, little was known about their interaction with Candida albicans.
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