Macrophages Accumulate in the Gut Mucosa of Untreated HIV-infected Patients | Zendy

Kristina Allers | Zendy; Michael Fehr | Zendy; Kristina Conrad | Zendy; Hans–Jörg Epple | Zendy; Dirk Schürmann | Zendy; Anika GeelhaarKarsch | Zendy; Katina Schinnerling | Zendy; Verena Moos | Zendy; Thomas Schneider | Zendy

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Macrophages Accumulate in the Gut Mucosa of Untreated HIV-infected Patients

Author(s) -

Kristina Allers,

Michael Fehr,

Kristina Conrad,

Hans–Jörg Epple,

Dirk Schürmann,

Anika GeelhaarKarsch,

Katina Schinnerling,

Verena Moos,

Thomas Schneider

Publication year - 2013

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jit547

Subject(s) - ccr2 , immunology , ccl2 , proinflammatory cytokine , monocyte , biology , intestinal mucosa , chemokine , secretion , macrophage , cxcl10 , inflammation , ccl5 , immune system , microbiology and biotechnology , medicine , t cell , chemokine receptor , il 2 receptor , biochemistry , in vitro

Mucosal macrophages are involved in the maintenance of epithelial barrier integrity and the elimination of invading pathogens. Although an intestinal barrier defect and microbial translocation are hallmarks of human immunodeficiency virus (HIV) infection, recent data on gut mucosal macrophages in HIV infection are sparse.

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