Open AccessComparison of the Live Attenuated Yellow Fever Vaccine 17D-204 Strain to Its Virulent Parental Strain Asibi by Deep Sequencing
Author(s) -
Andrew S. Beck,
Robert B. Tesh,
Thomas G. Wood,
Steven G. Widen,
Kate D. Ryman,
Alan D.T. Barrett
Publication year - 2013
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jit546
Subject(s) - strain (injury) , virology , virulence , attenuated vaccine , yellow fever , biology , virus , virus strain , microbiology and biotechnology , gene , genetics , anatomy
The first comparison of a live RNA viral vaccine strain to its wild-type parental strain by deep sequencing is presented using as a model the yellow fever virus (YFV) live vaccine strain 17D-204 and its wild-type parental strain, Asibi.
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