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Value of Plasmodium falciparum Histidine-Rich Protein 2 Level and Malaria Retinopathy in Distinguishing Cerebral Malaria From Other Acute Encephalopathies in Kenyan Children
Author(s) -
Symon M. Kariuki,
Evelyn Gitau,
Samson Gwer,
Henry Karanja,
Edward Chengo,
Michael Kazungu,
Britta C. Urban,
Charles R. Newton
Publication year - 2013
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jit500
Subject(s) - cerebral malaria , malaria , parasitemia , plasmodium falciparum , medicine , immunology , plasmodium berghei , virology , biology , pediatrics
The diagnosis of cerebral malaria is problematic in malaria-endemic areas because encephalopathy in patients with parasitemia may have another cause. Abnormal retinal findings are thought to increase the specificity of the diagnosis, and the level of histidine-rich protein 2 (HRP2) may reflect the parasite biomass.

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