Seroepidemiology of Hepatitis E Virus Infection in an Urban Population in Zambia: Strong Association With HIV and Environmental Enteropathy
Author(s) -
Cato Jacobs,
Clarence Chiluba,
C. Phiri,
M M Lisulo,
Mumba Chomba,
Philip C. Hill,
Samreen Ijaz,
Paul Kelly
Publication year - 2013
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jit409
Subject(s) - hepatitis e virus , seroprevalence , medicine , enteropathy , immunology , hepatitis e , coinfection , population , odds ratio , antibody , serology , virology , virus , biology , environmental health , genotype , biochemistry , disease , gene
Hepatitis E virus (HEV) infection causes major epidemics of infectious hepatitis, with high mortality rates in pregnant women. Recent reports indicate that HEV coinfections with human immunodeficiency virus (HIV) may have a more protracted course. However, the impact of HEV infections in communities heavily affected by HIV remains poorly studied. We set out to examine age-related seroprevalence in a community where we have previously carried out studies on environmental enteropathy.
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