Experimentally Induced Blood-Stage Plasmodium vivax Infection in Healthy Volunteers
Author(s) -
James McCarthy,
Paul Griffin,
Silvana Sekuloski,
A. Taylor Bright,
Rebecca J. Rockett,
David Looke,
Suzanne Elliott,
David M. Whiley,
Theo P. Sloots,
Elizabeth A. Winzeler,
Katharine R. Trenholme
Publication year - 2013
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jit394
Subject(s) - gametocyte , malaria , plasmodium vivax , artemether/lumefantrine , parasite hosting , biology , virology , immunology , plasmodium (life cycle) , polymerase chain reaction , parasitemia , parasitology , medicine , plasmodium falciparum , artemisinin , gene , genetics , world wide web , computer science , zoology
Major impediments to development of vaccines and drugs for Plasmodium vivax malaria are the inability to culture this species and the extreme difficulty in undertaking clinical research by experimental infection.
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