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Plasmodium falciparum is responsible for severe malaria, including pregnancy-associated malaria (PAM). During intra-erythrocytic maturation, the infected erythrocyte (iE) membrane is modified by insertion of parasite-derived proteins, primarily consisting of variant surface antigens such as P. falciparum erythrocyte membrane protein-1.

the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases

Differential Protein Expression Profiles Between Plasmodium falciparum Parasites Isolated From Subjects Presenting With Pregnancy-Associated Malaria and Uncomplicated Malaria in Benin