Reduced Risk of Disease During Postsecondary Dengue Virus Infections
Author(s) -
Sandra Olkowski,
Brett M. Forshey,
Amy C. Morrison,
Claudio Rocha,
Stalin Vilcarromero,
Eric S. Halsey,
Tadeusz J. Kochel,
Thomas W. Scott,
Steven T. Stoddard
Publication year - 2013
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jit273
Subject(s) - dengue virus , dengue fever , virology , transmission (telecommunications) , serotype , population , disease , immunology , biology , medicine , environmental health , electrical engineering , engineering
Antibodies induced by infection with any 1 of 4 dengue virus (DENV) serotypes (DENV-1-4) may influence the clinical outcome of subsequent heterologous infections. To quantify potential cross-protective effects, we estimated disease risk as a function of DENV infection, using data from longitudinal studies performed from September 2006 through February 2011 in Iquitos, Peru, during periods of DENV-3 and DENV-4 transmission.
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