A FimH Inhibitor Prevents Acute Bladder Infection and Treats Chronic Cystitis Caused by Multidrug-Resistant Uropathogenic Escherichia coli ST131 | Zendy

Makrina Totsika | Zendy; Maria Kostakioti | Zendy; Thomas J. Hannan | Zendy; Mathew Upton | Zendy; Scott A. Beatson | Zendy; James W. Janetka | Zendy; Scott J. Hultgren | Zendy; Mark A. Schembri | Zendy

Open Access

A FimH Inhibitor Prevents Acute Bladder Infection and Treats Chronic Cystitis Caused by Multidrug-Resistant Uropathogenic Escherichia coli ST131

Author(s) -

Makrina Totsika,

Maria Kostakioti,

Thomas J. Hannan,

Mathew Upton,

Scott A. Beatson,

James W. Janetka,

Scott J. Hultgren,

Mark A. Schembri

Publication year - 2013

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jit245

Subject(s) - escherichia coli , microbiology and biotechnology , fimbria , bacterial adhesin , multiple drug resistance , clone (java method) , antibiotics , escherichia coli infection , urinary system , pilus , acute cystitis , biology , medicine , gene , biochemistry

Escherichia coli O25b:H4-ST131 represents a predominant clone of multidrug-resistant uropathogens currently circulating worldwide in hospitals and the community. Urinary tract infections (UTIs) caused by E. coli ST131 are typically associated with limited treatment options and are often recurrent.

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