Analysis of Nontypeable Haemophilus influenzae Phase-Variable Genes During Experimental Human Nasopharyngeal Colonization | Zendy

Jessica Poole | Zendy; Eric D. Foster | Zendy; Kathryn Chaloner | Zendy; Jason R. Hunt | Zendy; Michael P. Jennings | Zendy; Thomas Bair | Zendy; Kevin L. Knudtson | Zendy; Erik D. Christensen | Zendy; Robert S. Munson | Zendy; Patricia Winokur | Zendy; Michael A. Apicella | Zendy

Open Access

Analysis of Nontypeable Haemophilus influenzae Phase-Variable Genes During Experimental Human Nasopharyngeal Colonization

Author(s) -

Jessica Poole,

Eric D. Foster,

Kathryn Chaloner,

Jason R. Hunt,

Michael P. Jennings,

Thomas Bair,

Kevin L. Knudtson,

Erik D. Christensen,

Robert S. Munson,

Patricia Winokur,

Michael A. Apicella

Publication year - 2013

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jit240

Subject(s) - haemophilus influenzae , microbiology and biotechnology , colonization , pasteurellaceae , biology , virology , antibiotics

Studies of nontypeable Haemophilus influenzae (NTHi) have demonstrated that a number of genes associated with infectivity have long repeat regions associated with phase variation in expression of the respective gene. The purpose of this study was to determine the genes that underwent phase variation during a 6-day period of experimental human nasopharyngeal colonization.

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