Plasma Viral MicroRNA Profiles Reveal Potential Biomarkers for Chronic Active Epstein–Barr Virus Infection | Zendy

Yoshihiko Kawano | Zendy; Seiko Iwata | Zendy; Junichi Kawada | Zendy; Kensei Gotoh | Zendy; Michio Suzuki | Zendy; Yuka Torii | Zendy; Seiji Kojima | Zendy; Hiroshi Kimura | Zendy; Yoshinori Ito | Zendy

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Plasma Viral MicroRNA Profiles Reveal Potential Biomarkers for Chronic Active Epstein–Barr Virus Infection

Author(s) -

Yoshihiko Kawano,

Seiko Iwata,

Junichi Kawada,

Kensei Gotoh,

Michio Suzuki,

Yuka Torii,

Seiji Kojima,

Hiroshi Kimura,

Yoshinori Ito

Publication year - 2013

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jit222

Subject(s) - virology , virus , epstein–barr virus infection , epstein–barr virus , microrna , biology , viral load , immunology , medicine , gene , genetics

Chronic active Epstein-Barr virus (CAEBV) infection has high mortality and morbidity, and biomarkers for disease severity and prognosis are required. MicroRNAs (miRNAs) are small noncoding RNAs, and EBV encodes multiple miRNAs. Because plasma contains sufficiently stable miRNAs, circulating EBV-associated miRNA profiles were investigated as novel biomarkers in CAEBV infection.

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