Alternative Mutational Pathways to Intermediate Resistance to Vancomycin in Methicillin-Resistant Staphylococcus aureus | Zendy

Céline Vidaillac | Zendy; Susana Gardete | Zendy; Ryan Tewhey | Zendy; George Sakoulas | Zendy; Glenn W. Kaatz | Zendy; Warren E. Rose | Zendy; Alexander Tomasz | Zendy; Michael J. Rybak | Zendy

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Alternative Mutational Pathways to Intermediate Resistance to Vancomycin in Methicillin-Resistant Staphylococcus aureus

Author(s) -

Céline Vidaillac,

Susana Gardete,

Ryan Tewhey,

George Sakoulas,

Glenn W. Kaatz,

Warren E. Rose,

Alexander Tomasz,

Michael J. Rybak

Publication year - 2013

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jit127

Subject(s) - vancomycin , biology , mutant , daptomycin , staphylococcus aureus , microbiology and biotechnology , rpob , methicillin resistant staphylococcus aureus , mutation , point mutation , antibacterial agent , genetics , gene , antibiotics , bacteria , 16s ribosomal rna

We used 2 in vitro experimental systems to compare phenotypic and genotypic changes that accompany selection of mutants of methicillin-resistant Staphylococcus aureus (MRSA) strain JH1 with low-level vancomycin resistance similar to the type found in vancomycin-intermediate S. aureus (VISA).

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