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Therapeutic Vaccination Expands and Improves the Function of the HIV-Specific Memory T-Cell Repertoire
Author(s) -
Joseph P. Casazza,
Kathryn Bowman,
Selorm Adzaku,
Emily C. Smith,
Mary E. Enama,
Robert T. Bailer,
David A. Price,
Emma Gostick,
Ingelise J. Gordon,
David R. Ambrozak,
Martha Nason,
Mario Roederer,
Charla Andrews,
Frank Maldarelli,
Ann Wiegand,
Mary F. Kearney,
Deborah Persaud,
Carrie Ziemniak,
Raphaël Gottardo,
Julie E. Ledgerwood,
Barney S. Graham,
Richard A. Koup
Publication year - 2013
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jit098
Subject(s) - vaccination , virology , immunology , ctl* , cytotoxic t cell , hiv vaccine , vaccine trial , cd8 , viral load , biology , aids vaccines , epitope , t cell , immunity , medicine , immune system , virus , antigen , genetics , in vitro
The licensing of herpes zoster vaccine has demonstrated that therapeutic vaccination can help control chronic viral infection. Unfortunately, human trials of immunodeficiency virus (HIV) vaccine have shown only marginal efficacy.

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