Open AccessAttenuation of Live Respiratory Syncytial Virus Vaccines Is Associated With Reductions in Levels of Nasal Cytokines
Author(s) -
Ruth A. Karron,
Bhagvanji Thumar,
Elizabeth Schappell,
Ursula J. Buchholz,
Peter L. Collins
Publication year - 2013
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jit089
Subject(s) - respiratory system , respiratory tract , medicine , virus , lower respiratory tract infection , respiratory tract infections , virology , immunology
Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract illness (LRTI) in children. Several promising live-attenuated RSV vaccines are in development. Defining additional markers of attenuation could enhance clinical trials.
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