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Clinical Evidence for the Role of Trichomonas vaginalis in Regulation of Secretory Leukocyte Protease Inhibitor in the Female Genital Tract
Author(s) -
Jill S. Huppert,
Bin Huang,
Chen Chen,
Hassan Y. Dawood,
Rai. Fichorova
Publication year - 2013
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jit039
Subject(s) - trichomonas vaginalis , genital tract , trichomonas , microbiology and biotechnology , protease inhibitor (pharmacology) , immunology , protease , biology , trichomonas vaginitis , female circumcision , medicine , physiology , enzyme , gynecology , virus , biochemistry , antiretroviral therapy , viral load
Secretory leukocyte protease inhibitor (SLPI) is responsible for regulating inflammatory damage to and innate and adaptive immune responses in the vaginal mucosa. Depressed cervicovaginal SLPI levels have been correlated with both Trichomonas vaginalis infection and poor reproductive health outcomes.

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