Open AccessElevated Interleukin 8 and T-Helper 1 and T-Helper 17 Cytokine Levels Prior to Antiretroviral Therapy in Participants Who Developed Immune Reconstitution Inflammatory Syndrome During ACTG A5164
Author(s) -
Philip Grant,
Lauren Komarow,
Michael M. Lederman,
Savita Pahwa,
Andrew Zolopa,
Janet Andersen,
David M. Asmuth,
Sridevi Devaraj,
Richard B. Pollard,
Aaron Richterman,
Sudheesh Pilakka Kanthikeel,
Irini Sereti
Publication year - 2012
Publication title -
the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jis604
Subject(s) - immune reconstitution inflammatory syndrome , immunology , cytokine , medicine , immune system , logistic regression , tumor necrosis factor alpha , biomarker , iris (biosensor) , interleukin , t cell , antiretroviral therapy , virus , viral load , biology , biochemistry , computer security , biometrics , computer science
Immune reconstitution inflammatory syndrome (IRIS) reflects an aberrant immune response that can develop in human immunodeficiency virus-infected patients initiating antiretroviral therapy (ART). Its pathogenesis remains unclear.