Open AccessPreviously Transmitted HIV-1 Strains Are Preferentially Selected During Subsequent Sexual Transmissions
Author(s) -
Andrew D. Redd,
Aleisha Collinson-Streng,
Nikolaos Chatziandreou,
Caroline E. Mullis,
Oliver Laeyendecker,
Craig Martens,
Stacy Ricklefs,
Noah Kiwanuka,
Phyu Hninn Nyein,
Tom Lutalo,
M. Kate Grabowski,
Xiangrong Kong,
Jordyn Manucci,
Nelson Sewankambo,
Maria J. Wawer,
Ronald H. Gray,
Stephen F. Porcella,
Anthony S. Fauci,
Manish Sagar,
David Serwadda,
Thomas C. Quinn
Publication year - 2012
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jis503
Subject(s) - biology , virology , sanger sequencing , transmission (telecommunications) , genetic diversity , population , sexual transmission , polymerase chain reaction , genetics , viral load , lentivirus , dna sequencing , virus , human immunodeficiency virus (hiv) , viral disease , gene , demography , microbicide , sociology , electrical engineering , engineering
A genetic bottleneck is known to exist for human immunodeficiency virus (HIV) at the point of sexual transmission. However, the nature of this bottleneck and its effect on viral diversity over time is unclear.
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