Symptomatic Infection and Detection of Vaccine and Vaccine-Reassortant Rotavirus Strains in 5 Children: A Case Series | Zendy

J Boom | Zendy; Leila C. Sahni | Zendy; Daniel C. Payne | Zendy; R Gautam | Zendy; Freda C. Lyde | Zendy; Slavica Mijatovic-Rustempasic | Zendy; Michael D. Bowen | Zendy; J. E. Tate | Zendy; Marcia A. Rench | Zendy; Jon R. Gentsch | Zendy; Umesh D. Parashar | Zendy; Carol J. Baker | Zendy

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Symptomatic Infection and Detection of Vaccine and Vaccine-Reassortant Rotavirus Strains in 5 Children: A Case Series

Author(s) -

J Boom,

Leila C. Sahni,

Daniel C. Payne,

R Gautam,

Freda C. Lyde,

Slavica Mijatovic-Rustempasic,

Michael D. Bowen,

J. E. Tate,

Marcia A. Rench,

Jon R. Gentsch,

Umesh D. Parashar,

Carol J. Baker

Publication year - 2012

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jis490

Subject(s) - rotavirus , rotavirus vaccine , virology , norovirus , reoviridae , rotavirus infections , vaccination , medicine , feces , biology , virus , microbiology and biotechnology

Vaccine or vaccine-reassortant rotavirus strains were detected in fecal specimens from 5 of 106 (4.7%) immunocompetent children who required treatment for rotavirus gastroenteritis at a large pediatric hospital in Texas in 2009-2010. Four strains were related to pentavalent rotavirus vaccine, whereas one was related to monovalent rotavirus vaccine. The contribution of these strains to each patient's illness was unclear given that 2 patients had prominent respiratory symptoms and 2 were concurrently infected with another pathogen (group F adenovirus and norovirus). Continued monitoring is necessary to assess the role of vaccine strains and vaccine-reassortant strains in pediatric rotavirus infections.

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