Low-Level Plasmodium falciparum Blood-Stage Infection Causes Dendritic Cell Apoptosis and Dysfunction in Healthy Volunteers
Author(s) -
Tonia Woodberry,
Gabriela Minigo,
Kim A. Piera,
Fiona H. Amante,
Alberto PinzónCharry,
Michael F. Good,
J. Alejandro López,
Christian Engwerda,
James McCarthy,
Nicholas M. Anstey
Publication year - 2012
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jis366
Subject(s) - parasitemia , plasmodium falciparum , malaria , immunology , biology , immune system , parasite hosting , in vivo , immunity , dendritic cell , medicine , microbiology and biotechnology , world wide web , computer science
Dendritic cells (DCs) are highly specialized antigen-presenting cells that are crucial for initiation of immune responses. During naturally acquired malaria, DC number and function is reduced.
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