Open AccessThe Prostanoid 15-Deoxy-Δ12,14-Prostaglandin-J2 Reduces Lung Inflammation and Protects Mice Against Lethal Influenza Infection
Author(s) -
Alexandre Cloutier,
Isabelle Marois,
Diane Cloutier,
Catherine Verreault,
André M. Cantin,
Martin Richter
Publication year - 2012
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jir804
Subject(s) - inflammation , prostanoid , immune system , immunology , lung , medicine , lung infection , biology , prostaglandin
Growing evidence indicates that influenza pathogenicity relates to altered immune responses and hypercytokinemia. Therefore, dampening the excessive inflammatory response induced after infection might reduce influenza morbidity and mortality.
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