Limited Immunogenicity of HIV CD8+ T-Cell Epitopes in Acute Clade C Virus Infection
Author(s) -
Mopo Radebe,
K. Narayanan Nair,
Fundisiwe Chonco,
Karen Bishop,
Jaclyn K. Wright,
Mary van der Stok,
Ingrid V. Bassett,
Zenele Mncube,
Marcus Altfeld,
Bruce D. Walker,
Thumbi Ndung’u
Publication year - 2011
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jir394
Subject(s) - immunogenicity , virology , epitope , virus , biology , clade , cd8 , immune system , human immunodeficiency virus (hiv) , immunology , antigen , gene , phylogenetics , genetics
Human immunodeficiency virus type 1 (HIV-1)-specific CD8(+) responses contribute to the decline in acute peak viremia following infection. However, data on the relative immunogenicity of CD8(+) T-cell epitopes during and after acute viremia are lacking.
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