Placental Malaria-Associated Inflammation Disturbs the Insulin-like Growth Factor Axis of Fetal Growth Regulation | Zendy

Alexandra J. Umbers | Zendy; Philippe Boeuf | Zendy; Caroline Clapham | Zendy; Danielle I. Stanisic | Zendy; Francesca Baiwog | Zendy; Ivo Müeller | Zendy; Peter Siba | Zendy; Christopher L. King | Zendy; James G. Beeson | Zendy; Jocelyn D. Glazier | Zendy; Stephen J. Rogerson | Zendy

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Placental Malaria-Associated Inflammation Disturbs the Insulin-like Growth Factor Axis of Fetal Growth Regulation

Author(s) -

Alexandra J. Umbers,

Philippe Boeuf,

Caroline Clapham,

Danielle I. Stanisic,

Francesca Baiwog,

Ivo Müeller,

Peter Siba,

Christopher L. King,

James G. Beeson,

Jocelyn D. Glazier,

Stephen J. Rogerson

Publication year - 2011

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jiq080

Subject(s) - fetus , inflammation , placenta , medicine , biology , endocrinology , plasmodium falciparum , growth factor , insulin like growth factor , somatomedin , malaria , receptor , pregnancy , immunology , genetics

The pathogenetic mechanisms of fetal growth restriction associated with placental malaria are largely unknown. We sought to determine whether placental malaria and related inflammation were associated with disturbances in the insulin-like growth factor (IGF) axis, a major regulator of fetal growth.

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