Open AccessReduced Pathogenicity and Transmission Potential of Omicron BA.1 and BA.2 Sublineages Compared with the Early Severe Acute Respiratory Syndrome Coronavirus 2 D614G Variant in Syrian Hamsters
Author(s) -
Wen Su,
Ka Tim Choy,
Hongcang Gu,
Sin Fun Sia,
Ka Man Cheng,
Sarea Islam Nuha Nizami,
Pavithra Krishnan,
Yuet Mai Ng,
Lydia Dai Jia Chang,
Yingzhi Liu,
Samuel Cheng,
Malik Peiris,
Leo L M Poon,
John M. Nicholls,
Hui-Ling Yen
Publication year - 2022
Publication title -
the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jiac276
Subject(s) - hamster , transmission (telecommunications) , viral load , biology , virology , transmissibility (structural dynamics) , mesocricetus , respiratory system , virus , microbiology and biotechnology , anatomy , physics , vibration isolation , quantum mechanics , electrical engineering , vibration , engineering
The epidemiological advantage of Omicron variant is evidenced by its rapid spread and the ability to outcompete prior variants. Among Omicron sublineages, early outbreaks were dominated by BA.1, while BA.2 has gained dominance since February 2022. The relative pathogenicity and transmissibility of BA.1 and BA.2 have not been fully defined.