Open AccessSafety and Immunogenicity of a Respiratory Syncytial Virus Prefusion F Vaccine When Coadministered With a Tetanus, Diphtheria, and Acellular Pertussis Vaccine
Author(s) -
James T. Peterson,
Agnieszka Zareba,
David Fitzpatrick,
Brandon Essink,
Daniel A. Scott,
Kena A. Swanson,
Dhawal Chelani,
David Radley,
David A. Cooper,
Kathrin U. Jansen,
Philip R. Dormitzer,
William C. Gruber,
Alejandra Gurtman
Publication year - 2021
Publication title -
the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jiab505
Subject(s) - tetanus , toxoid , diphtheria , medicine , immunogenicity , whooping cough , immunology , vaccination , immunization , immune system
Prevention of respiratory syncytial virus (RSV) disease in infants is an unmet vaccine need, and maternal immunization is a potential strategy to address this need. This study evaluated concomitant administration of RSV stabilized prefusion F subunit vaccine (RSVpreF) and tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine adsorbed (Tdap) in healthy, nonpregnant women 18‒49 years of age.