The Role of Molecular Testing in Pediatric Meningitis Surveillance in Southern and East African Countries, 2008–2017
Author(s) -
Mig du Plessis,
Linda de Gouveia,
Cesar Mavacala Freitas,
Negga Asamene Abera,
Budiaki Sylvie Lula,
Julia Liliane Raboba,
Aquino Albino Nhantumbo,
Elana Jantjies,
Jeannine Uwimana,
Nomcebo Phungwayo,
Gugu Maphalala,
Gilbert Masona,
John Muyombe,
David Mugisha,
Esther Nalumansi,
Moses Odongkara,
Chileshe LukwesaMusyani,
Ruth Nakazwe,
Vongai Dondo,
John Macharaga,
Goitom Weldegebriel,
Jason M. Mwenda,
Fatima Serhan,
Adam L. Cohen,
Fernanda C. Lessa,
Anne von Gottberg
Publication year - 2021
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jiab092
Subject(s) - neisseria meningitidis , meningitis , serotype , odds ratio , streptococcus pneumoniae , medicine , haemophilus influenzae , confidence interval , blood culture , polymerase chain reaction , microbiological culture , haemophilus , virology , microbiology and biotechnology , immunology , biology , pediatrics , antibiotics , bacteria , biochemistry , genetics , gene
As part of the global Invasive Bacterial Vaccine-Preventable Diseases Surveillance Network, 12 African countries referred cerebrospinal fluid (CSF) samples to South Africa's regional reference laboratory. We evaluated the utility of real-time polymerase chain reaction (PCR) in detecting and serotyping/grouping Haemophilus influenzae, Neisseria meningitidis, and Streptococcus pneumoniae (HNS).
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