Impact of Vaccination on Haemophilus influenzae Type b Carriage in Healthy Children Less Than 5 Years of Age in an Urban Population in Nepal | Zendy

Sonu Shrestha | Zendy; Lisa Stockdale | Zendy; Madhav Chandra Gautam | Zendy; Meeru Gurung | Zendy; Shuo Feng | Zendy; Pratistha Maskey | Zendy; Simon Kerridge | Zendy; Sarah Kelly | Zendy; Merryn Voysey | Zendy; Bhishma Pokhrel | Zendy; Piyush Rajbhandari | Zendy; Stephen Thorson | Zendy; Bibek Khadka | Zendy; Ganesh Shah | Zendy; Karin S Scherer | Zendy; Dominic F. Kelly | Zendy; David R. Murdoch | Zendy; Shrijana Shrestha | Zendy; Andrew J. Pollard | Zendy

Open Access

Impact of Vaccination on Haemophilus influenzae Type b Carriage in Healthy Children Less Than 5 Years of Age in an Urban Population in Nepal

Author(s) -

Sonu Shrestha,

Lisa Stockdale,

Madhav Chandra Gautam,

Meeru Gurung,

Shuo Feng,

Pratistha Maskey,

Simon Kerridge,

Sarah Kelly,

Merryn Voysey,

Bhishma Pokhrel,

Piyush Rajbhandari,

Stephen Thorson,

Bibek Khadka,

Ganesh Shah,

Karin S Scherer,

Dominic F. Kelly,

David R. Murdoch,

Shrijana Shrestha,

Andrew J. Pollard

Publication year - 2021

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jiab072

Subject(s) - medicine , hib vaccine , carriage , vaccination , pediatrics , diphtheria , haemophilus influenzae , population , asymptomatic , immunization , virology , conjugate vaccine , immunology , environmental health , antibiotics , pathology , antigen , biology , microbiology and biotechnology

Reduction in detection of asymptomatic carriage of Haemophilus influenzae type b (Hib) can be used to assess vaccine impact. In Nepal, routine vaccination against Hib in children at 6, 10, and 14 weeks of age was introduced in 2009. Before vaccine introduction, Hib carriage was estimated at 5.0% among children aged <13 years in Nepal, with higher rates among children under 5. Large-scale evaluation of Hib carriage in children has not been investigated since the introduction of the pentavalent diphtheria-tetanus-pertussis/Hib/hepatitis B (DTP-Hib-HepB) vaccine in Nepal.

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