Open AccessA coupled non-Fickian model of a cardiovascular drug delivery system
Author(s) -
J.A. Ferreira,
Jahed Naghipoor,
Paula de Oliveira
Publication year - 2015
Publication title -
mathematical medicine and biology a journal of the ima
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 45
eISSN - 1477-8602
pISSN - 1477-8599
DOI - 10.1093/imammb/dqv023
Subject(s) - library science , classics , medicine , history , computer science
A coupled non-Fickian model of a cardiovascular drug delivery system using a biodegradable drug-eluting stent is proposed. The numerical results are obtained using an implicit-explicit finite-element method. The influence of vessel stiffness on the transport of drug eluted from the stent is analysed. The results presented in this paper suggest new perspectives to adapt the drug delivery profile to the needs of the patient.
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