Exposure-Response Relationships during Free-Access Intravenous Alcohol Self-Administration in Nondependent Drinkers: Influence of Alcohol Expectancies and Impulsivity
Author(s) -
B Stangl,
Vatsalya Vatsalya,
Molly R. Zametkin,
Megan Cooke,
Martin H. Plawecki,
Sean O’Connor,
Vijay A. Ramchandani
Publication year - 2016
Publication title -
the international journal of neuropsychopharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 107
eISSN - 1469-5111
pISSN - 1461-1457
DOI - 10.1093/ijnp/pyw090
Subject(s) - impulsivity , alcohol , self administration , alcohol dependence , psychology , alcohol consumption , addiction , clinical psychology , expectancy theory , medicine , psychiatry , social psychology , biochemistry , chemistry
Self-administration is a hallmark of all addictive drugs, including alcohol. Human laboratory models of alcohol self-administration have characterized alcohol-seeking behavior and served as surrogate measures of the effectiveness of pharmacotherapies for alcohol use disorders. Intravenous alcohol self-administration is a novel method that assesses alcohol exposure driven primarily by the pharmacological response to alcohol and may have utility in characterizing unique behavioral and personality correlates of alcohol-seeking and consumption.
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