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In our recent review and meta-analyses of reports of long-term trials of treatments for major depressive disorder patients, we noted that remarkably little potentially relevant and interesting clinical information was included in most reports (Sim et al., 2015). This limitation seemed particularly remarkable in long-term studies carried out at great effort and expense. In general, reports of clinical trials in various disorders appear to focus rather narrowly on outcomes for which the trials were designed, usually rates of relapse or recurrence of a particular illness (Baldessarini, 2013).In an effort to evaluate this impression more closely, we re-reviewed the reports cited in our review (Sim et al., 2015), focusing specifically on any indications of suicidal behaviors, which are of particular interest with major mood disorder patients. We recorded any comment or data pertaining to suicidal events, including completed suicides, attempts or self-injuries, or suicidal ideation typically significant enough as to require removal from the trial. Exposure times include not …

Suicidal Risks in Reports of Long-Term Treatment Trials for Major Depressive Disorder: Table 1.