Hippocampal PPARδ Overexpression or Activation Represses Stress-Induced Depressive Behaviors and Enhances Neurogenesis | Zendy

MiaoJin Ji | Zendy; Xuben Yu | Zendy; Zhen-lin Mei | Zendy; Yunqi An | Zendy; Susu Tang | Zendy; Mei Hu | Zendy; Yan Long | Zendy; Mingxing Miao | Zendy; Qinghua Hu | Zendy; Hongbin Sun | Zendy; Lingyi Kong | Zendy; Hao Hong | Zendy

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Hippocampal PPARδ Overexpression or Activation Represses Stress-Induced Depressive Behaviors and Enhances Neurogenesis

Author(s) -

MiaoJin Ji,

Xuben Yu,

Zhen-lin Mei,

Yunqi An,

Susu Tang,

Mei Hu,

Yan Long,

Mingxing Miao,

Qinghua Hu,

Hongbin Sun,

Lingyi Kong,

Hao Hong

Publication year - 2015

Publication title -

the international journal of neuropsychopharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.897

H-Index - 107

eISSN - 1469-5111

pISSN - 1461-1457

DOI - 10.1093/ijnp/pyv083

Subject(s) - neurogenesis , hippocampal formation , neuroprotection , downregulation and upregulation , hippocampus , peroxisome proliferator activated receptor , endocrinology , neural stem cell , dentate gyrus , agonist , medicine , receptor , neuroscience , chemistry , biology , microbiology and biotechnology , stem cell , biochemistry , gene

Emerging data have demonstrated that peroxisome proliferator-activated receptor δ (PPARδ) activation confers a potentially neuroprotective role in some neurodegenerative diseases. However, whether PPARδ is involved in depression is unknown.

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