Effects of Varenicline on Neural Correlates of Alcohol Salience in Heavy Drinkers | Zendy

Vatsalya Vatsalya | Zendy; Joshua L. Gowin | Zendy; Melanie L. Schwandt | Zendy; Reza Momenan | Zendy; Marion A. Coe | Zendy; Megan Cooke | Zendy; Daniel W. Hommer | Zendy; Selena E. Bartlett | Zendy; Markus Heilig | Zendy; Vijay A. Ramchandani | Zendy

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Effects of Varenicline on Neural Correlates of Alcohol Salience in Heavy Drinkers

Author(s) -

Vatsalya Vatsalya,

Joshua L. Gowin,

Melanie L. Schwandt,

Reza Momenan,

Marion A. Coe,

Megan Cooke,

Daniel W. Hommer,

Selena E. Bartlett,

Markus Heilig,

Vijay A. Ramchandani

Publication year - 2015

Publication title -

the international journal of neuropsychopharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.897

H-Index - 107

eISSN - 1469-5111

pISSN - 1461-1457

DOI - 10.1093/ijnp/pyv068

Subject(s) - varenicline , functional magnetic resonance imaging , placebo , psychology , craving , smoking cessation , alcohol , self administration , alcohol use disorder , alcohol dependence , anesthesia , nicotine , medicine , addiction , psychiatry , neuroscience , pathology , biochemistry , chemistry , alternative medicine

Preclinical and emerging clinical evidence indicates that varenicline, a nicotinic partial agonist approved for smoking cessation, attenuates alcohol seeking and consumption. Reductions of alcohol craving have been observed under varenicline treatment and suggest effects of the medication on alcohol reward processing, but this hypothesis remains untested.

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