Association Study Indicates a Protective Role of Phosphatidylinositol-4-Phosphate-5-Kinase against Tardive Dyskinesia | Zendy

Olga Fedorenko | Zendy; A.J.M. Loonen | Zendy; F. Lang | Zendy; Valentina A. Toshchakova | Zendy; E.G. Boyarko | Zendy; A. Semke | Zendy; Н. А. Бохан | Zendy; Н. В. Говорин | Zendy; Lyubomir I. Aftanas | Zendy; Svetlana А. Ivanova | Zendy

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Association Study Indicates a Protective Role of Phosphatidylinositol-4-Phosphate-5-Kinase against Tardive Dyskinesia

Author(s) -

Olga Fedorenko,

A.J.M. Loonen,

F. Lang,

Valentina A. Toshchakova,

E.G. Boyarko,

A. Semke,

Н. А. Бохан,

Н. В. Говорин,

Lyubomir I. Aftanas,

Svetlana А. Ivanova

Publication year - 2014

Publication title -

the international journal of neuropsychopharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.897

H-Index - 107

eISSN - 1469-5111

pISSN - 1461-1457

DOI - 10.1093/ijnp/pyu098

Subject(s) - tardive dyskinesia , dyskinesia , neurotoxicity , single nucleotide polymorphism , antipsychotic , medicine , schizophrenia (object oriented programming) , pharmacology , psychiatry , genetics , biology , gene , toxicity , genotype , parkinson's disease , disease

Tardive dyskinesia is a disorder characterized by involuntary muscle movements that occur as a complication of long-term treatment with antipsychotic drugs. It has been suggested to be related to a malfunctioning of the indirect pathway of the motor part of the cortical-striatal-thalamic-cortical circuit, which may be caused by oxidative stress-induced neurotoxicity.

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