Open AccessNeurofilament Light Chain Is a Novel Biomarker for Major Depression and Related Executive Dysfunction
Author(s) -
MuHong Chen,
Yuli Liu,
HsinWei Kuo,
ShihJen Tsai,
JuWei Hsu,
KaiLin Huang,
Pei-Chi Tu,
YaMei Bai
Publication year - 2021
Publication title -
international journal of neuropsychopharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 107
eISSN - 1469-5111
pISSN - 1461-1457
DOI - 10.1093/ijnp/pyab068
Subject(s) - proinflammatory cytokine , executive dysfunction , biomarker , depression (economics) , medicine , major depressive disorder , psychology , bipolar disorder , oncology , psychiatry , cognition , inflammation , neuropsychology , biology , biochemistry , macroeconomics , economics
Evidence suggests that major depressive disorder is related to neuroaxonal injury and that neurofilament light chain (NfL) is a biomarker of neuroaxonal injury. In addition, proinflammatory cytokines have been reported to be associated with major depression and neuroaxonal injury.